WinPOPT
 

Optimization for Population PKPD Study Design

 

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Features
Features of WinPOPT & POPT include:
  • Optimization for multiple response models (e.g. PKPD or Parent-Metabolite)
  • Optimization for models defined as ODEs
  • Optimization for multiple responses (e.g. 2 or more drugs administered simultaneously)
  • Optimization including:
    • fixed sampling times
    • multiple study arms
    • constrained clinic visit times
    • lockout between consecutive samples
    • sampling windows
    • adding prior information

WinPOPT screen shots:
 

Main GUI: You can specify the model, enter the design and choose your optimization method.

Model GUI: Specify the details of the model. You can enter the model mean parameters, between subject variability values and model, random variability and select which parameters are not to be estimated.

Design GUI: Specify the details of the design. Enter the number of subjects, dose, dose interval and design points.

Copyright WinPOPT 2006